Our Vision
Across Pharmaceuticals Inc is a neurological disease-focused biotechnology company focused on developing CNS-targeted molecules as novel neuroregenerative therapies for unmet medical needs in neuroinflammation and demyelinating diseases
To accelerate the development of our two assets
a)Epidermal growth factor (EGF)-platform as a treatment supporting neuroregeneration and decreasing microglial inflammation
b)Advancing our xB3 platform for targeted treatment of auto-immune neuroinflammation, with optimized BBB crossing of repurposed compounds generating new drug with new IP, with first objective to combine EGF with xB3
Optimise drug development to provide a rapid exit to investors
Maximise development efficiency by exploiting orphan drug status in niche indications
R&D Pipeline
Research&Development Pipeline
•ACROSS PHARMACEUTICALS pipeline aims at strengthening the offer of innovative therapeutic solutions for neurodegenerative disorders
•Currently in a preclinical phase, the pipeline should advance as quickly as possible towards the first human administration
Indications
Optic neuritis related to multiple sclerosis
Epidermal growth factor (EGF) as a novel treatment for neuro-regeneration
Chronic Inflammatory Demyelinating
Polyneuropathy
a rare neurological disorder in which there is inflammation of nerve roots and peripheral nerves and destruction of the fatty protective covering of the nerve fibers
Guillain Barré Syndrome (GBS)
GBS a rare and progressive disease characterized by inflammation of the nerves causing muscle weakness, sometimes progressing to complete paralysis
Alzheimer Disease
Alzheimer is a neurodegenerative disorder where deposits of proteins form amyloid plaques and tau tangles in the brain
Meet the team
Prof Ferdinando Nicoletti
co-founder and Member of the Board of Across Pharmaceuticals
Prof Francois Curtin
co-founder and Member of the Board of Across Pharmaceuticals
Dr Imene Kouidmi
co-founder and Member of the Board of Across Pharmaceuticals
Prof Alois Bernhard Lang
co-founder and Member of the Board of Across Pharmaceuticals
Dr Mei Mei Tian
Senior Scientific Advisor to Across Pharmaceuticals
